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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH2
All Species:
13.64
Human Site:
S725
Identified Species:
30
UniProt:
O75038
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75038
NP_055453.2
1416
154668
S725
Q
L
N
R
A
K
F
S
A
N
G
G
C
G
Y
Chimpanzee
Pan troglodytes
XP_001149239
1685
188441
K711
Q
L
N
R
A
K
F
K
A
N
G
S
C
G
Y
Rhesus Macaque
Macaca mulatta
XP_001085424
1423
155915
S732
Q
L
N
R
A
K
F
S
A
N
G
G
C
G
Y
Dog
Lupus familis
XP_546733
1387
151432
S709
Q
L
N
R
A
K
F
S
A
N
G
N
C
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
A2AP18
1501
164279
S806
Q
L
N
R
A
K
F
S
A
N
G
D
C
G
Y
Rat
Rattus norvegicus
Q62688
1096
122754
Y486
F
A
F
V
A
S
E
Y
P
L
I
L
C
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q2VRL0
637
72514
K27
I
D
F
D
S
T
V
K
L
L
E
K
L
H
M
Frog
Xenopus laevis
Q32NH8
758
87399
K148
D
W
F
Q
K
A
D
K
N
K
D
G
R
M
N
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
N174
Y
L
R
R
A
D
Q
N
Q
D
G
K
M
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
E700
Q
L
N
L
G
I
F
E
Y
N
A
R
S
G
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
R800
Q
L
L
R
A
K
F
R
A
N
G
S
C
G
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.4
94
78.7
N.A.
77.2
21.2
N.A.
N.A.
21.2
24.7
24.5
N.A.
24.2
N.A.
N.A.
26.4
Protein Similarity:
100
59.9
95.4
82.9
N.A.
81.6
36.7
N.A.
N.A.
30.7
35.3
35
N.A.
40.3
N.A.
N.A.
35.7
P-Site Identity:
100
86.6
100
93.3
N.A.
93.3
13.3
N.A.
N.A.
0
6.6
33.3
N.A.
46.6
N.A.
N.A.
80
P-Site Similarity:
100
86.6
100
93.3
N.A.
93.3
13.3
N.A.
N.A.
6.6
13.3
46.6
N.A.
46.6
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
73
10
0
0
55
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
64
0
0
% C
% Asp:
10
10
0
10
0
10
10
0
0
10
10
10
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
10
0
0
10
0
0
0
0
% E
% Phe:
10
0
28
0
0
0
64
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
64
28
0
64
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
10
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
10
55
0
28
0
10
0
19
0
0
0
% K
% Leu:
0
73
10
10
0
0
0
0
10
19
0
10
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
10
% M
% Asn:
0
0
55
0
0
0
0
10
10
64
0
10
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
64
0
0
10
0
0
10
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
10
64
0
0
0
10
0
0
0
10
10
0
0
% R
% Ser:
0
0
0
0
10
10
0
37
0
0
0
19
10
10
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
10
10
0
0
0
0
0
73
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _